Single-Cell Proteomics

Tsinghua University's Jiang Rui research group has released ProtCell, a foundation model for single-cell proteomics pretrained on roughly 380 million cells across 98 public datasets, capable of mapping cell states and inferring unmeasured protein expression to support drug discovery and virtual-cell construction. The paper also reports a full pretraining reproduction on Moore Threads' MTT S5000 accelerator, with key quantitative metrics deviating only about 0.2% from mainstream international GPU platforms.